RIFM fragrance ingredient safety assessment, Eugenol, CAS Registry Number 97-53-0.
نویسندگان
چکیده
The use of this material under current use conditions is supported by the existing information. This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity, skin sensitization potential, as well as, environmental safety. Reproductive toxicity was determined to have the most conservative systemic exposure derived NO[A]EL of 230 mg/kg/day. A gavage multigenerational continuous breeding study conducted in rats on a suitable read across analog resulted in a MOE of 12,105 while considering 22.6% absorption from skin contact and 100% from inhalation. A MOE of >100 is deemed acceptable.
منابع مشابه
RIFM fragrance ingredient safety assessment, methyl dihydrojasmonate, CAS registry number 24851-98-7.
RIFM fragrance ingredient safety assessment, methyl dihydrojasmonate, CAS registry number 24851-98-7 A.M. Api a, D. Belsito b, S. Bhatia a, M. Bruze c, P. Calow d, M.L. Dagli e, W. Dekant f, A.D. Fryer g, L. Kromidas a,*, S. La Cava a, J.F. Lalko a, A. Lapczynski a, D.C. Liebler h, Y. Miyachi i, V.T. Politano a, G. Ritacco a, D. Salvito a, J. Shen a, T.W. Schultz j, I.G. Sipes k, B. Wall a, D.K...
متن کاملRIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde, CAS registry number 122-40-7.
RIFM fragrance ingredient safety assessment, α-amylcinnamaldehyde, CAS registry number 122-40-7 A.M. Api a, D. Belsito b, S. Bhatia a, M. Bruze c, P. Calow d, M.L. Dagli e, W. Dekant f, A.D. Fryer g, L. Kromidas a,*, S. La Cava a, J.F. Lalko a, A. Lapczynski a, D.C. Liebler h, Y. Miyachi i, V.T. Politano a, G. Ritacco a, D. Salvito a, J. Shen a, T.W. Schultz j, I.G. Sipes k, B. Wall a, D.K. Wil...
متن کاملRIFM fragrance ingredient safety assessment, Linalyl hexanoate, CAS Registry Number 7779-23-9.
RIFM fragrance ingredient safety assessment, Linalyl hexanoate, CAS Registry Number 7779-23-9 A.M. Api a, D. Belsito b, S. Bhatia a, M. Bruze c, P. Calow d, M.L. Dagli e, W. Dekant f, A.D. Fryer g, L. Kromidas a,*, S. La Cava a, J.F. Lalko a, A. Lapczynski a, D.C. Liebler h, Y. Miyachi i, V.T. Politano a, G. Ritacco a, D. Salvito a, J. Shen a, T.W. Schultz j, I.G. Sipes k, B. Wall a, D.K. Wilcox a
متن کاملRIFM fragrance ingredient safety assessment, Benzyl acetate, CAS Registry Number 140-11-4.
RIFM fragrance ingredient safety assessment, Benzyl acetate, CAS Registry Number 140-11-4 A.M. Api a, , D. Belsito , S. Bhatia , M. Bruze , P. Calow , M.L. Dagli , W. Dekant , A.D. Fryer , L. Kromidas , S. La Cava , J.F. Lalko , A. Lapczynski , D.C. Liebler , Y. Miyachi , V.T. Politano , G. Ritacco , D. Salvito , T.W. Schultz , J. Shen , I.G. Sipes , B. Wall , D.K. Wilcox a a Research Institute...
متن کاملRIFM fragrance ingredient safety assessment, Benzyl alcohol, CAS Registry Number 100-51-6.
RIFM fragrance ingredient safety assessment, Benzyl alcohol, CAS Registry Number 100-51-6 A.M. Api a, , D. Belsito , S. Bhatia , M. Bruze , P. Calow , M.L. Dagli , W. Dekant , A.D. Fryer , L. Kromidas , S. La Cava , J.F. Lalko , A. Lapczynski , D.C. Liebler , V.T. Politano , G. Ritacco , D. Salvito , T.W. schultz , J. Shen , I.G. Sipes , B. Wall , D.K. Wilcox a a Research Institute for Fragranc...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
دوره 97S شماره
صفحات -
تاریخ انتشار 2016